1. Which one of the following conditions is most likely to produce a microcytosis on blood film examination

    1. Alcohol excess
    2. Thalassaemia
    3. Autoimmune haemolytic anaemia
    4. Vitamin B12 deficiency
    5. Hypothyroidism

  2. A 59 year-old-man is referred to the haematology clinic with a month-3 history of progressive lethargy. He complains of recurrent sore throat and has recently noticed bleeding from his gums when he brushes his teeth. He has also noticed that he bruises easily. He appears pale but examination is otherwise nonremarkable. lnvestigations reveal the following : What is the most likely diagnosis

    1. Non-Hodgkin lymphoma
    2. Acute myeloid leukaemia (AML)
    3. Chronic myeloid leukaemia (CML)
    4. Myelodysplastic syndrome
    5. Aplastic anaemia

  3. AII of the following features relate to Sickle Cell Disease Except

    1. Splenic atrophy
    2. Positive Coomb's test
    3. Very high hemoglobin S
    4. Hemolytic anemia
    5. Painful vaso-occlusive crises

  4. all the following drugs may exacerbate myasthenia gravis except

    1. cefutaxime.
    2. ciprofioxacin.
    3. .betablockers
    4. D-penicillamine
    5. .erythromycine

  5. A year-old-23 university student is diagnosed with meningitis of bacterial etiology. The cause has been assigned as bacterial. What is the most likely finding on CSF analysis

    1. ,Lymphocytes decreased ,protein increased glucose
    2. ,Lymphocytes normal ,protein normal glucose
    3. ,Polymorphs increased ,protein decreased glucose
    4. ,Polymorphs normal ,protein normal glucose
    5. ,Lymphocytes increased ,protein normal glucose

  6. regarding treatment of multiple sclerosis one of following is wrong

    1. Commonest side effect of INF-B is reaction at injection site.
    2. sun exposure is useful
    3. Cladribine is a disease modifying drug.
    4. Amantidine may be useful for primary fatigue of multiple sclerosis.
    5. dietary 3-omiga is recommended.

  7. A year-old-32 man presents with ataxia, dysarthria and visual disturbance. On examination you note absent lower limb tendon reflexes and an upgoing plantar You also note absence of joint position and vibration sense in his lower limbs A visual examination demonstrates nystagmus and pale-coloured optic discs. What is the most likely diagnosis

    1. Friedreich ataxia
    2. Syringobulbia
    3. Syringomyelia
    4. Cauda equina lesion
    5. Spinal cord compression

  8. which one of the following cause coma without focal neurological deficit

    1. hyperthermia
    2. cerebral infarction
    3. epidural and subdural hemorrhage
    4. brain abscess
    5. intracerebral hemorrhage

  9. 20 years male with history of ataxia, spastic lower limbs, Ve+ Bilat. Cerebellar signs. bilat. Extensor planter, no pes cavus with Ve+ family history the, most likely diagnosis is

    1. Spinocerebellar Ataxia
    2. Vitamin B12 deficiency
    3. Vitamin E deficiency
    4. Fridrich Ataxia
    5. Ataxia Telangiectasia

  10. all the following are used in status epilepticus: EXCEPT

    1. lorazepam
    2. heparin
    3. phenobarbital
    4. glucose
    5. diazepam

  11. regarding pathogenesis of multiple sclerosis one of following is correct

    1. more common in higher socioeconomic classes.
    2. single gene responsible.
    3. no role for environmental factor.
    4. only humeral sector of immune system involved
    5. aggregation in families not common.

  12. Causes of CIDP include all except

    1. diabetes mellitis
    2. multiple myeloma
    3. meningitis
    4. alcohol
    5. lymphoma

  13. COOMB'S TEST is positive in

    1. Hereditary spherocytosis
    2. Warm autoimmune hemolytic anemia
    3. Thalassemia minor
    4. Phosphate-6-Glucose Dehydrogenase deficiency
    5. lron deficiency anemia

  14. First-line drug treatment for status epilepticus: is

  15. Serum aquaporine 4 antibody is Ve+ in

  16. ln severe lupus nephritis the following are true. except

  17. A 2O-year-old man returns from a trip to istanbul. He complains of pain in his knees as well as pain on passing urine. What is the most likely diagnosis

  18. What type of red cell abnormalities are expected in iron deficiency anemia

  19. Marked splenomegaly could be seen in any of the following EXCEPT

  20. Regarding paracetamol poisoning which one of the following statement is correct